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After the operation of simple pylorus ligation (Shay rat), the pH of post-operative gastric juice became lower as the t ime elapsed, especially more than 10 hours af ter the operation, the pH were less than 2.0. In this period, the esophagitis were found in 10 rats macroscopically and 16 rats histologically out of 17 rats. In all cases of Shay rats,… (More)