F I Proĭmina

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Radioimmunoassays were used to determine the LH, FSH, estradiol and progesterone content in the female rat blood in the morning (10-12 a. m.) and in the evening (5-6 p. m.). An identical circadian rhythm of the secretion of the above hormones with an increase in the level of estradiol in the morning and that of gonadotropin and progesterone in the evening(More)
I.m. administration of estradiol benzoat in physiological doses decreased 3-fold the lutropin secretion and follitropin secretion by one third, in ovariectomised rats. The same dose in intact rats decreases the lutropin level in the blood and gonadoliberin contents in the medial eminence by the negative feedback mechanism. In 4-6 hrs after injection the(More)
Luliberin (LH-RH) was assayed radioimmmunologically in the hypothalamic fragments taken from male and female rats, intact or with isolated mediobasal hypothalamus. An increased amount of LH-RH was found in the fragments containing organum vasculosum of the lamina terminals (OVLT) and taken from intact males. LH-RH amount was negligible in isolated parts of(More)
Complete disappearance of adrenergic fibers in the rat uterus is only possible after complete removal of ovaries along with ovarian plexus, transection of the uterus-vaginal connexion and removal of a portion of sympathetic nervous trunk. "Long" adrenergic neurons situated in spinal sympathetic ganglia, seem not to be the only source of sympathetic(More)
In female rats with normal estrous cycle, in the proestrus phase, a significant decrease of the serotonine level was revealed in the anterior and medio-basal parts of the hypothalamus which coincided with ascent of the releasing factor for gonadotropic hormones in the hypothalamus and for gonadotropins in the hypophysis. The dophamine level in the(More)
In the androgen-sterile rats given 10-250 mug of testosterone-propionate there was observed at the early postnatal period a reduction in the LH-RP level in the hypothalamus, of the LH in the hypophysis and the blood, of the weight of the ovaries and of the corporal luteum count in them, as well as an increase in the dopamine level in the anterior portion of(More)
Daily administration of 0.25 mg reserpine during 14 days reduces the noradrenaline and dopamine level in the hypothalamus by 21--47 per cent and the LH level in the blood. The amount of Gn-RH in the supra-and retrochiasmatic portions of the hypothalamus is significantly increased thereby indicating an inhibition of the RH release into the blood of portal(More)