F H Bosch

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It has been accepted that neuroinflammation, oxidative stress and glial activation are involved in the central sensitization underlying neuropathic pain. Vimang is an aqueous extract of Mangifera indica L. traditionally used in Cuba for its analgesic, anti-inflammatory, antioxidant and immunomodulatory properties. Several formulations are available, and(More)
Central sensitization theory has been defined as pivotal for understanding the excitability changes in central neurons following peripheral inflammation or neuropathic injury. Considerable evidence has demonstrated that activation of the N-methyl-D-aspartate (NMDA) subtype of glutamate receptors and subsequent nitric oxide (NO) production are the key in(More)
We performed a retrospective evaluation of the use of carbohydrate deficient transferrin (CDT) in a general hospital, for diagnosing alcohol abuse. The high specificity for the CDT test and lower sensitivity as reported in the literature were confirmed. Alcohol anamnesis proved rather often to be incomplete. In intensive care medicine, the CDT investigation(More)
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