F. Dumas-Bouchiat

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The modulation of developmental biochemical pathways by mechanical cues is an emerging feature of animal development, but its evolutionary origins have not been explored. Here we show that a common mechanosensitive pathway involving β-catenin specifies early mesodermal identity at gastrulation in zebrafish and Drosophila. Mechanical strains developed by(More)
This paper presents fast switching RF microelectromechanical systems (MEMS) capacitors with measured switching times between 150-400 ns. By introducing bent sides on a planar microbeam, it is shown experimentally that the resonance frequency of aluminum bridges is increased by a factor of 25 compared to standard RF MEMS components. In addition, this(More)
Interactions between a micro-magnet array and living cells may guide the establishment of cell networks due to the cellular response to a magnetic field. To manipulate mesenchymal stem cells free of magnetic nanoparticles by a high magnetic field gradient, we used high quality micro-patterned NdFeB films around which the stray field's value and direction(More)
Animal development consists of a cascade of tissue differentiation and shape change. Associated mechanical signals regulate tissue differentiation. Here we demonstrate that endogenous mechanical cues also trigger biochemical pathways, generating the active morphogenetic movements shaping animal development through a mechanotransductive cascade of Myo-II(More)
Thèse dirigée par Gilbert REYNE et co-encadrée par Frédéric DUMAS-BOUCHIAT Abstract The range of applications for magnetic micro-and nano-particles is constantly expanding, in particular in medicine and biology. A number of applications involve particle trapping and deviation under the effect of a magnetic field and field gradient. In most publications, the(More)
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