F. De Ambroggi

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Both the nucleus accumbens (NAc) and basolateral amygdala (BLA) contribute to learned behavioral choice. Neurons in both structures that encode reward-predictive cues may underlie the decision to respond to such cues, but the neural circuits by which the BLA influences reward-seeking behavior have not been established. Here, we test the hypothesis that the(More)
Suppression of ill-timed or competing actions optimizes goal-directed behaviors. Diminished inhibitory control over such actions is a central feature of such disorders as impulsivity, obesity, and drug addiction. The ventromedial prefrontal cortex (vmPFC) is involved in suppression of unreinforced actions. Using reversible inactivation in rats, we(More)
The nucleus accumbens (NAc) is involved in many reward-related behaviors. The NAc has two major components, the core and the shell. These two areas have different inputs and outputs, suggesting that they contribute differentially to goal-directed behaviors. Using a discriminative stimulus (DS) task in rats and inactivating the NAc by blocking excitatory(More)
Reward-seeking behavior is controlled by neuronal circuits that include the basolateral nucleus of amygdala (BLA), medial prefrontal cortex (mPFC), nucleus accumbens (NAc) and ventral tegmental area. Using a discriminative stimulus (DS) task in which an intermittently presented cue (DS) directs rats to make an operant response for sucrose, we previously(More)
Cue-elicited phasic changes in firing of nucleus accumbens (NAc) neurons can facilitate reward-seeking behavior. Here, we test the hypothesis that the medial prefrontal cortex (mPFC), which sends a dense glutamatergic projection to the NAc core, contributes to NAc neuronal firing responses to reward-predictive cues. Rats trained to perform an operant(More)
1 . I N T R O D U C T I O N Microrobotics researches require to operate on autonomous devices with simple design and limited costs and energy consumption, even if this fact limits the possible tasks of each single robot. In the last few years the interest in micro mechatronic systems is increasing and several different kind of microrobots have been designed(More)
Although many studies in neuroscience are based on comparing neuronal responses to single, isolated sensory or motor events, multiple events frequently occur in close temporal proximity in freely moving animals. This often obscures the precise temporal correlation between each event and the relevant brain activity. By simulating neuronal responses in(More)
The ventral pallidum (VP) is posited to contribute to reward seeking by conveying upstream signals from the nucleus accumbens (NAc). Yet, very little is known about how VP neuron responses contribute to behavioral responses to incentive cues. Here, we recorded activity of VP neurons in a cue-driven reward-seeking task previously shown to require neural(More)
Ghazizadeh A, Fields HL, Ambroggi F. Isolating event-related neuronal responses by deconvolution. J Neurophysiol 104: 1790–1802, 2010. First published July 14, 2010; doi:10.1152/jn.00389.2010. Although many studies in neuroscience are based on comparing neuronal responses to single, isolated sensory or motor events, multiple events frequently occur in close(More)
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