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The mutagenicity of sodium nitrite was assayed by in vivo and in vitro experiments. The in vivo experiments were carried out in male rats and mice intragastrically treated twice, with an interval of 24 h, with nitrite in doses of 1.72, 5.18, 15.55 and 46.66 mg/kg body weight and in male rabbits treated with the same doses of nitrite administered daily in(More)
In three children communities covered by a virological study enteroviruses could be isolated from 19.3% of the stool samples, 52.3% of the sewage samples and 9.7% of the samples taken from different objects and surfaces. The isolates belonged to 14 enterovirus serotypes, Coxsackie viruses being predominant. There was a good concordance between the serotypes(More)
An epidemic outbreak of viral meningitis mainly caused by Coxsackie B3 virus is described. Characteristic of the outbreak was the involvment of a large number of infants under 1 year of age (about 1/4 of the total number of cases) and the elevated incidence of encephalitis symptoms, as compared with the meningitis outbreak caused by echovirus 4 in 1973.