F Bruce Coles

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The largest recorded epidemic of sporotrichosis in the United States occurred in 1988 and involved a total of 84 cases in 15 states. All cases were associated with Wisconsin-grown sphagnum moss. Twenty-one clinical isolates of Sporothrix schenckii and 69 environmental isolates of Sporothrix spp. from the epidemic were characterized and compared. The(More)
OBJECTIVE To describe the epidemiologic features of an outbreak of influenza A that occurred in a skilled nursing home although over 90 percent of the resident population had previously received influenza vaccine. DESIGN Retrospective cohort study. SETTING Skilled nursing home facility in western New York State. PATIENTS Nursing home residents and(More)
Institutional risk factors associated with the occurrence of nosocomial respiratory or gastrointestinal disease outbreaks in 1992 were examined in a case-cohort study of New York State nursing homes conducted in 1993. Facility size, staffing patterns, and employee sick leave policies were the principal effects found in an unconditional logistic regression(More)
Immunophenotypic analysis of paraffin-embedded tissues of lymphoproliferative disorders has been facilitated by recent developments of monoclonal antibodies that react with epitopes that survive histologic processing. Leukocyte common antigen (LCA) antibody has made a significant contribution to the immunocytochemical separation of non-Hodgkin's lymphomas(More)
In the spring of 1988, the largest documented US outbreak of cutaneous sporotrichosis to date occurred, with 84 cases among persons from 15 states who were exposed to Wisconsin-grown sphagnum moss used in packing evergreen tree seedlings. In New York State, 13 cases occurred among 109 forestry workers. All 13 cases occurred among 76 workers who had handled(More)
BACKGROUND To treat chlamydial infection, the Centers for Disease Control and Prevention recommends either a single dose of azithromycin or a 7-day course of doxycycline. Cost is a concern with the single-dose regimen; compliance is a concern with the multidose regimen. GOAL To compare the use-effectiveness of azithromycin and doxycycline for preventing(More)
The reliability of eight self-reported risk factors as criteria for screening women for Chlamydia trachomatis was evaluated in four family planning clinics in New York State that serve diverse populations. In all, 8,920 women were screened in these clinics; the rates of infection ranged from 2% to 7%. Results of multivariate analyses showed that age was the(More)
Population estimates are generally drawn from one point in time to study disease trends over time; changes in population characteristics over time are usually not assessed and included in the study design. We evaluated whether population characteristics remained static and assessed the degree of population shifts over time. The analysis was based on the New(More)
BACKGROUND Gonorrhea persists despite nationwide disease control measures. Research has not focused on the longitudinal impact of community characteristics on gonorrhea. The authors assessed the association between community demographic and socioeconomic changes and gonorrhea rates. METHODS Gonorrhea incident cases reported in 1992-1993 and 2001-2002 were(More)
OBJECTIVE The objective of this study was to estimate the effectiveness of partner notification (PN) by linking measures of PN with the gonorrhea incidence rate in New York State exclusive of New York City. STUDY DESIGN Gonorrhea cases were identified from the Communicable Disease Confidential Case Reports system. Case interview data were obtained from(More)