F. Bachmair

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Over-expression of the proto-oncogene HER-2 (c-erbB-2/neu) in ovarian, endometrial, and mammary carcinoma is an indicator of poor prognosis. Interactions between the epidermal growth factor (EGF) receptor and the HER-2 protein have been described. The aim of this study was to elucidate the effects of EGF on HER-2 expression. In the human ovarian carcinoma(More)
Retinoids and Interferons have been demonstrated to synergistically amplify the inhibition of proliferation in cultured breast cancer cells. Recently we reported that interferon-gamma (IFN-gamma) modulates the action of retinoic acid (RA): IFN-gamma increased expression of retinoic acid receptor-gamma (RAR-gamma) and suppressed the increase of retinoic acid(More)
Driven by technological advancements, gesture interfaces have recently found their way into vehicular prototypes of various kind. Unfortunately, their application is less than perfect and detailed information about preferred gesture execution regions, spatial extent, and time behavior are not available yet. Providing car (interior) manufacturer with gesture(More)
Vitamin A and its biologically active derivatives, retinal and retinoic acid, play an important role in vision, are required for reproduction, act as morphogenic agents during embryonic development, and regulate the growth and differentiation of a wide variety of cell types throughout the life of an organism. The biological action of retinoic acid and(More)
A method for the quantitative analysis of specific mRNA species by reverse transcription-polymerase chain reaction (RT-PCR) and subsequent detection of products by means of ion-pair reversed-phase high-performance liquid chromatography (IP-RP-HPLC) on alkylated micropellicular polystyrene-divinylbenzene particles has been developed. For RT-PCR, we used the(More)
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