F. Armani

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It has been demonstrated that sleep deprivation is associated with altered expression of genes related to metabolic processes, response to stress and inflammation, circadian sleep/wake cycles, regulation of cell proliferation and various signaling pathways. However, the molecular mechanisms underlying these changes remain poorly understood. Thus, the(More)
BACKGROUND Previous studies have suggested that manic states and sleep deprivation could contribute to the pathophysiology of bipolar disorder (BD) through protein kinase C (PKC) signaling abnormalities. Moreover, adjunctive therapy has become a standard strategy in the management of BD patients who respond poorly to current pharmacological treatments. (More)
  • Sergio Tufik, Profa Dra, Levy Monica, Andersen, Martha Maria, Bernarde +52 others
  • 2016
Milhares de livros grátis para download. Influence of long-term food restriction associate or not it paradoxical sleep deprivation in the sleep architecture and sexual behavior of male rats. A todos os professores do curso de Pós-Graduação do Departamento de Psicobiologia, pelas importantes contribuições para minha formação acadêmica. pela ajuda e amizade(More)
Preliminary data on the efficacy of tamoxifen in reducing manic symptoms of bipolar disorder (BD) suggest that this agent may be a potential treatment for the management of this psychiatric disorder. However, the antimanic properties of tamoxifen have not been fully elucidated, hampering the development and/or use of mood-stabilising drugs that may share(More)
OBJECTIVE Since blood viscosity (BV) is one of the most important factors determining blood flow, this study aimed to investigate the possible correlation between increased blood viscosity and reduction of regional cerebral blood flow (rCBF) in healthy ageing. METHODS Male subjects were distributed in two groups: "young", aged 20-30 (27 volunteers), or(More)
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