Fátima Sánchez Cabo

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BACKGROUND Hereditary Angioedema due to C1-Inhibitor deficiency (HAE types I and II) is a monogenic disease characterized by sudden, self-limited episodes of cutaneous and mucosal swelling due to local deregulation of vascular permeability. Despite its monogenic pattern of inheritance, HAE exhibits great clinical variability and low genotype/phenotype(More)
Microarray technology is becoming an essential tool in functional genomics. The possibility of monitoring the expression level of thousands of genes simultaneously, as the response to a particular biological condition, gives to the biologists the chance to widen the aims of their experiments and opens a door to the understanding of cellular transcription(More)
One of the major limitations associated with platinum use is the resistance that almost invariably develops in different tumor types. In the current study, we sought to identify epigenetically regulated microRNAs as novel biomarkers of platinum resistance in lung and ovarian cancers, the ones with highest ratios of associated
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