Ezra Allen

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Desmogleins are members of the cadherin superfamily which form the core of desmosomes. In vitro studies indicate that the cytoplasmic domain of desmogleins associates with plakoglobin; however, little is known about the role of this domain in desmosome recognition or assembly in vivo, or about the possible relation of desmoglein mutations to epidermal(More)
The increase in eosinophils at the site of antigen challenge has been used as evidence to suggest that this cell type plays a role in the pathophysiology of asthma. Aberrant production of several different cytokines, particularly interleukin (IL)-5, has been shown to result in eosinophilia. IL-5 influences the development and maturation of eosinophils in a(More)
1. The general course of prenatal growth in the mouse, the guinea pig, and the chick can be expressed by straight line relations between the logarithms of the weight and age only when age is counted from the beginning of the embryo proper. 2. This is interpreted as showing that the manner of growth before the beginning of the embryo proper is essentially(More)
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