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Diabetes mellitus (DM) and obesity are believed to be risk factors for colorectal cancer in humans. In experiment 1, male nondiabetic Long-Evans Tokushima Otsuka (LETO) rats and Otsuka Long-Evans Tokushima Fatty (OLETF) rats, a model animal of type 2 DM, were whole-body X-irradiated (4 Gy) at 6 and 8 weeks of age and euthanized at 78 weeks of age (n=15,(More)
The surface of ovarian oocytes is evenly covered with finger-like microvilli about 1 micron long. Penetration of capcitated spermatozoa in the zona pellucida apparently occurs after acrosome reaction and though a narrow slitmmorulae are constituted of rounded blastomeres, usually of similar size and microvillous covering. A few blastomeres may be smaller(More)
Female rats raised from birth under a light/dark (LD) or constant light (LL) regimen were given injections at either 24, 29, 33 or 35 days of age of either 5 IU PMSG or 0.1 ml saline. Two days following PMSG or saline injection, the rats were given injections of either 1,000 ng synthetic gonadotropin releasing hormone (GnRH) or 0.1 ml saline. Blood samples(More)
Ejaculated baboon sperm was observed by scanning electron microscopy. The plasma membrane was generally smooth except on the acrosome where it was probably slightly wrinkled. The head was short, oval, paddle-shaped and tapering at its anterior end. The anterior segment of the acrosome was surrounded by a marginal thickening; the postacrosomal region was(More)
A 90-day oral toxicity test in rats was performed to evaluate the toxicity of 2-tetradecylcyclobutanone (2-tDCB), a unique radiolytic product of stearic acid. Six-week-old male and female F344 rats (n=15/group) were given 2-tDCB at concentrations of 0, 12, 60 and 300 ppm in a powder diet for 13 weeks. Slight dose-dependent increases in serum total protein(More)
Presents pathology in relation to the living patient. Rigorously updated to include new material on genetic disorders, immunity and hypersensitivity, the cell and body chemistry. Combining systemic and regional approaches, quality illustrations drawn specifically for the book, directly from dissected cats, depict structures in situ. Entirely revised and(More)
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