Eyassu Makonnen

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BACKGROUND Drug resistance monitoring is an important aspect of tuberculosis (TB) control. OBJECTIVE To determine the sensitivity of mycobacterial isolates from newly diagnosed pulmonary TB patients to first line anti-TB drugs in Addis Ababa. METHODS A survey on primary anti-tuberculosis drug resistance was conducted on smear positive pulmonary TB(More)
  • E Makonnen
  • Phytomedicine : international journal of…
  • 2000
The constipating and spasmolytic effects of Catha edulis Forsk (Khat) were investigated in whole mice and on isolated guinea pig ileum. D-amphetamine was employed in both experiments for comparison. The total distance travelled (expressed in percentage) by charcoal suspension in the gastrointestinal tract of mice was determined before and after khat(More)
OBJECTIVE This study aims at investigating the in vivo antiplasmodial activity of a traditionally used medicinal plant, Withania somnifera, L. Dunal, (Solanaceae). METHODS Rodent malaria parasite, Plasmodium berghei, 0.2 ml of x l0(7) parasites, was inoculated into Swiss albino mice intraperitoneally. Extracts were administered by intra gastric tube daily(More)
BACKGROUND Malaria is one of the most important infectious diseases in the World. The choice for the treatment is highly limited, and several of these may eventually be lost or compromised due to drug resistance. The use of plant medicine in the treatment of malaria and its various presentations is a common practice in many countries of Africa where the(More)
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