Ewout F W Courrech Staal

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BACKGROUND Tumour stroma ratio (TSR) in histological sections of resected oesophageal adenocarcinomas proved to be a prognostic factor for patients' survival. The objectives of this study were to assess inter- and intraobserver agreement for TSR scoring on biopsy material and to validate these biopsy results with the results derived from surgical specimens.(More)
OBJECTIVES The aim of this study was to retrospectively evaluate toxicity and efficacy of 3 chemoradiation regimens. METHODS Between 1997 and 2007, 94 patients with esophageal cancer were treated with chemoradiation in our institute. Treatment consisted of radiotherapy to 50 Gy in 25 fractions with concurrent cisplatin and 5-fluorouracil (group A, n =(More)
BACKGROUND Surgery alone for locally advanced oesophageal cancer is associated with low cure rates. The benefits and risks of neoadjuvant chemoradiation for patients with oesophageal cancer were evaluated. METHODS A systematic review of publications between 2000 and 2008 on neoadjuvant chemoradiation for oesophageal cancer was undertaken. RESULTS(More)
BACKGROUND Studies on quality of care for oesophageal cancer patients usually include only traditional outcome parameters. The aim of the study was to address quality of care in a broader perspective. METHODS Between 2003 and 2008, 821 oesophageal cancer patients were referred to our institute. Indicators to measure quality of care (i.e., process and(More)
OBJECTIVE To evaluate the prognostic value of the tumour stroma ratio (TSR) in resected adenocarcinoma of the oesophagus. BACKGROUND In the literature, a refinement of oesophageal cancer staging has been proposed. Recently, TSR has been identified as a histological characteristic of the tumour itself that proved to be a strong predictor for survival in(More)
OBJECTIVE Clinical outcomes have been investigated extensively in studies of esophageal cancer treatment. Less is known about long-term health-related quality of life outcomes. The aim of this study was to assess a range of health-related quality of life outcomes in patients with esophageal cancer treated with potentially curative intent at least 1 year(More)
BACKGROUND Quality-of-care indicators are measurable elements of practice performance that can assess the (change in) quality of the care provided. To date, the literature on quality-of-care indicators for oesophageal cancer surgery has not been reviewed. METHODS We performed a review of the literature on quality-of-care indicators for oesophageal cancer(More)
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