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Crystal-storing histiocytosis (CSH) with massive accumulation of particulate immunoglobulins is a rare phenomenon accompanying B-cell dyscrasias. In the reported case (M51), the disease presented as systemic CSH and later was proved to be a frank multiple myeloma. The aggregates of crystal-laden histiocytes were demonstrated in the bone marrow, lungs,(More)
Hemophagocytic lymphohistiocytosis (HLH) is a rare and potentially fatal disorder characterized by abnormal activation of macrophages and occurring in many conditions in all age group. It is also characterized by hemophagocytosis in the bone marrow and in the reticuloendothelial system (RES). The underlying mechanism of acquired HLH is associated with(More)
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