Ewa Grabowska

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The NOD2 gene has been associated with susceptibility to Crohn's disease and individuals with Crohn's disease are at increased risk for cancer at a number of organ sites. We studied the association between the 3020insC allele of the NOD2 gene and cancer among 2604 cancer patients and 1910 controls from Poland. Patients were diagnosed with one of twelve(More)
On the basis of literature data and own experience the authors review the current knowledge about the molecular basis of inherited predispositions for tumors. They hypothesize that in the near perspective 5–10 years studies using existing registry data/material and the latest novel technology will allow the identification of the molecular background for the(More)
The Wigler and Hicks group studies human cancer and genetic disorders from a population genomics perspective. The cancer effort focuses on breast and prostate cancer (the latter jointly with Lloyd Trotman) and involves col­ laborative clinical studies (with local, national, and inter­ national collaborators) to discover mutational patterns predicting(More)
The effect of clonidine, naphazoline and xylometazoline on analgesia induced by morphine, codeine, fentanyl and pentazocine, and on cataleptic effect of morphine, codine and fentanyl was studied in rats. The biochemical assays on the influence of four analgesics on the brain concentration and turnover of noradrenaline (NA) were also performed. It was found(More)
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