Evgeny Kanov

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In adult rodents stroke enhances neurogenesis resulting in the addition of neurons to forebrain regions such as striatum or cortex where postnatal neurogenesis under normal conditions plays a negligible role. In the cortex, new neurons are generated either from local cortical precursors that are activated by stroke or from precursors residing in the(More)
Pharmacokinetics of the new antiepileptic drug galodif was experimentally studied on rats. A single administration of the anticonvulsant is followed by slow elimination. A five-day administration leads to a significant acceleration of the drug elimination due to activation of the cytochrome P-450 dependent monooxygenase system of liver. After a 14-day(More)
Halodif (m-chlorobenzhydrylurea) possesses anticonvulsant [1, 2] and antiarrhythmogenic properties [3]. The administration of this drug leads to a significant increase in the content of microsomal protein, cytochrome P-450, and cytochrome b5 [4]. The experiments on rats revealed variations in the drug pharmacokinetics depending on the total duration of(More)
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