Evgeniy Ivashkin

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It has been demonstrated by us and other authors that first nervous cells in developing larvae from various trochozoan groups differentiate at the periphery. These pioneer neurons are distinguished by the set of characters. They are located outside the forming central ganglia; outgrowing fibers of central neurons use their processes as a “scaffolding”(More)
The neural crest represents a highly multipotent population of embryonic stem cells found only in vertebrate embryos. Acquisition of the neural crest during the evolution of vertebrates was a great advantage, providing Chordata animals with the first cellular cartilage, bone, dentition, advanced nervous system and other innovations. Today not much is known(More)
In a case study on development of larvae of Trochozoa species of different systematic positions, it was shown that peripheral neurons differentiated firstly. According to the characters of early peripheral neurons, in particular their localization in parts that differed from known zones of appearance of central ganglia, the difficult periphery of processes(More)
The state of gonads, age, structure of scales, and size of specimens of the resident lacustrine form of sock-eyed salmon—kokanee Onchorhynchus nerka—are analyzed. In stocked, previously fishless, lakes, there are specimens that have survived spawning and have remained active for a year or several years. No evidence was found of the possibility of repeated(More)
Chlorpromazine causes distinct defects in normal development of early cleaving embryos of gastropod pond snail (Lymnaea stagnalis L.) and teleost Eurasian weather loach (Misgurnus fossilis L.): a decrease in blastomere contact surfaces following the rounding in gastropod embryo and a reduction of cleaving blastodisk surface in teleost. Right after the(More)
The development of loach embryos is successfully regulated (normalized) after partial removal of the cytoplasm from one blastomere at the two- or four-cell stage or complete removal of one or two blastomeres at the stage of 8–16 cells. Using time-lapse video imaging and morphometric analysis, it has been shown that this regulation is a two-stage process. At(More)
Serotonin (5-HT) is known to induce a wide range of short-term and long-term (or delayed) effects. In the present paper we demonstrated that short time-window application of the 5-HT precursor 5-hydroxytryptophan during early cleavage stages results in both irreversible morphological malformation (exogastrulation) and distinct changes in behavior of young(More)
Serotonin (5.HT) is known to be functionally active during early development in both vertebrates and invertebrates. However, the presence of 5-HT and its synthesis and transport system has not yet been demonstrated in bivalve early development. The presence of 5-HT was immunochemically demonstrated at the cleavage stage of bivalve Mytilus trossulus. 5-HT(More)
Cultured cerebellar granule neurons (CGNs) are resistant to the toxic effect of ZnCl2 (0.005 mM, 3 h) and slightly sensitive to the effect of kainate (0.1 mM, 3 h). Simultaneous treatment of CGNs with kainate and ZnCl2 caused intensive neuronal death, which was attenuated by external acidosis (pH 6.5) or 5-(N-ethyl-N-isopropyl)amiloride (EIPA, Na+/H+(More)
Commercial importance and ability to live in a wide range of salinities have made the common mussel, Mytilus trossulus, a relevant model to study modulation of larval growth and development. We investigated the effects of various salinities combined with neomycin and ampicillin application on Mytilus larvae survival and growth. Both neomycin and ampicillin(More)