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Overcoming extractability hurdles of a 14C labeled taxane analogue milataxel and its metabolite from xenograft mouse tumor and brain tissues.
- H. Safarpour, P. Connolly, X. Tong, Mike Bielawski, Everett Wilcox
- Chemistry, Medicine
- Journal of pharmaceutical and biomedical analysis
- 5 April 2009
A productive extraction technique for milataxel (MAC-321, TL-139) in nude mice with various xenograft human tumors was developed by extracting analytes from tumors using a novel extraction procedure and analyzing samples by LC-MS. Expand