Radical addition to 1,4-benzoquinones: addition at O- versus C-atom.
Formation of aryl ethers via a unique radical addition to the oxygen atom of the enone system is the main reaction when bulky secondary and tertiary alkyl radicals are used.
Bare-minimum fluorous mixture synthesis of a stereoisomer library of 4,8,12-trimethylnonadecanols and predictions of NMR spectra of saturated oligoisoprenoid stereoisomers.
- Edmund A.-H. Yeh, Eveline Kumli, K. Damodaran, D. Curran
- ChemistryJournal of the American Chemical Society
- 30 January 2013
All four diastereomers of a typical saturated oligoisoprenoid, 4,8,12-trimethylnonadecanol, are made by an iterative three-step cycle with the aid of traceless thionocarbonate fluorous tags to encode…