Eva Valovičová

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Rat brain cortex slices were incubated in diluted sera obtained from patients with renal failure and from healthy persons. It was found that uraemic sera inhibited glucose uptake and the incorporation of14C-D-glucose into aspartate, glutamate and gamma-aminobutyrate (GABA). The concentration of these amino acids in the brain slices did not change.
Hyperthermic isolated limb perfusion (HILP) with melphalan (MH) as a standard cytotoxic drug has been performed in 28 patients suffering from malignant melanoma. MH has been administered by HILP via extracorporeal circulation system. The drug given locoregionally reduces subsequent toxicity of organs. For all that residues can leak into the systemic(More)