Eva Spies

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Among the diverse sets of nicotinic acetylcholine receptors (nAChRs), the alpha7 subtype is highly expressed in the hippocampus and cortex and is thought to play important roles in a variety of cognitive processes. In this review, we describe the properties of a novel biaryl diamine alpha7 nAChR agonist, A-582941. A-582941 was found to exhibit high-affinity(More)
Aspect-orientation has been capturing researcher's attention for the last few years. We have seen the birth of several aspect-oriented programming techniques and also the propagation of the aspect concept to the earlier stages of the software development process, such as requirements analysis and design. Our long-term goal is to extend aspect-orientation to(More)
Stereotactic cysto-ventricular shunting in three patients with congenital (subependymal cyst of the 3rd ventricle, subependymal cyst of the foramen of Monro, cyst of cavum septi pellucidi) and in a female patient with a large cystic suprasellar craniopharyngeoma is dealt with in this paper. The first operation was performed in May 1992 and the latest, being(More)
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