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  • T. Haas, Christoph H. Emmerich, +11 authors H. Walczak
  • Biology, Medicine
  • Molecular cell
  • 2009 (First Publication: 11 December 2009)
  • TNF is a key inflammatory cytokine. Using a modified tandem affinity purification approach, we identified HOIL-1 and HOIP as functional components of the native TNF-R1 signaling complex (TNF-RSC).Expand
  • Peter Dráber, Sebastián Kupka, +11 authors Henning Walczak
  • Medicine, Biology
  • Cell reports
  • 2015 (First Publication: 6 December 2015)
  • Summary Ubiquitination and deubiquitination are crucial for assembly and disassembly of signaling complexes. LUBAC-generated linear (M1) ubiquitin is important for signaling via various immuneExpand
  • Martin R Sprick, Eva Rieser, Heiko F. Stahl, Anne Grosse-Wilde, Markus Alexander Weigand, Henning Walczak
  • Biology, Medicine
  • The EMBO journal
  • 2002 (First Publication: 2 September 2002)
  • The involvement of the death adaptor protein FADD and the apoptosis-initiating caspase-8 in CD95 and TRAIL death signalling has recently been demonstrated by the analysis of the native death-inducingExpand
  • Birgit Washburn, Markus Alexander Weigand, +6 authors Henning Walczak
  • Biology, Medicine
  • The Journal of Immunology
  • 2003 (First Publication: 15 February 2003)
  • The Newcastle disease virus (NDV) has antineoplastic and immunostimulatory properties, and it is currently clinically tested in anticancer therapy. However, the tumoricidal mechanisms of NDV tumorExpand