Eva-Maria Holstein

Suggest Changes
Neal F. Lue16
David A. Lydall14
Constance I Nugent14
Victoria Lundblad12
Darren James Wilkinson12
10David A. Lydall
6H A Anderson
5Margherita Paschini
5Masahiro Terasawa
5Daichi Iwasaki

Filter Results:

  • Full text PDF available (6)

Publication Year

1961
2017
  • This year (1)
  • Last 5 years (3)
  • Last 10 years (5)

Publication Type

Co-author

Journals and Conferences

Data Set Used

Key Phrases

Learn More
Quantitative Fitness Analysis Shows That NMD Proteins and Many Other Protein Complexes Suppress or Enhance Distinct Telomere Cap Defects
To better understand telomere biology in budding yeast, we have performed systematic suppressor/enhancer analyses on yeast strains containing a point mutation in the essential telomere capping gene CDC13 (cdc13-1) or containing a null mutation in the DNA damage response and telomere capping gene YKU70 (yku70Δ). We performed Quantitative Fitness Analysis… (More)
Liver function tests among Michigan and Wisconsin dairy farmers.
Serum activity of SGOT, SGPT, LDH, and alkaline phosphatase was measured in 614 Michigan adults exposed to PBB and 141 Wisconsin adults not so exposed. The Michigan group had higher prevalence of abnormal SGOT (p less than 0.005) and SGPT (p less than 0.005). A clear sex difference was observed. Michigan men had a higher prevalence of abnormal SGPT (p less… (More)
Spermatogenesis in men exposed to polybrominated biphenyl (PBB).
Experience with other halogenated hydrocarbons, animal experiments, and individual complaints indicated that polybrominated biphenyl (PBB) might have an effect on human spermatogenesis. Analysis of semen from 52 PBB-exposed men as compared with analysis of semen from a control group of 52 men not exposed to PBB revealed no differences in the distribution of… (More)
Quantitative amplification of single-stranded DNA.
Single-stranded DNA (ssDNA) intermediates play an important role in processes such as DNA replication and homologous recombination, DNA damage responses, and DNA repair. Using quantitative amplification of ssDNA (QAOS), ssDNA arising during various cellular processes in complex genomes can be quantified at numerous single-copy and repetitive loci. QAOS is a… (More)
Interplay between Nonsense-Mediated mRNA Decay and DNA Damage Response Pathways Reveals that Stn1 and Ten1 Are the Key CST Telomere-Cap Components
A large and diverse set of proteins, including CST complex, nonsense mediated decay (NMD), and DNA damage response (DDR) proteins, play important roles at the telomere in mammals and yeast. Here, we report that NMD, like the DDR, affects single-stranded DNA (ssDNA) production at uncapped telomeres. Remarkably, we find that the requirement for Cdc13, one of… (More)
A simple technique for fat biopsy of PBB-exposed individuals.
A simple nonsurgical technique of obtaining fat samples by aspiration from the gluteal prominence was developed by Hirsh in 1960 and has been in use in our Nutrition Clinic at the Mount Sinai Hospital for several years. We have modified it for field use and the analysis of fat-soluble hydrocarbon residues. All the materials which will contain the fat sample… (More)
Port Allegany Asbestos Health Program: a community response to a public health problem.
The Port Allegany Asbestos Health Program (PAAHP) is a unique, community-run program that resulted from the successful cooperative efforts of a labor union, a corporation, community health care providers, and a medical school. PAAHP's goal is to develop a permanent community health organization that will use the most advanced existing knowledge to mitigate… (More)