Evaluation of the guinea pig monophasic action potential (MAP) assay in predicting drug-induced delay of ventricular repolarisation using 12 clinically documented drugs.Jens Kågström, Eva-Lena Sjögren, A K EricsonJournal of pharmacological and toxicological…2007INTRODUCTION While the dog in vivo model is commonly employed in the later phase of discovery for assessing drug-induced QT prolongation, an early screening assay is valuable when selecting compounds… (More)