Eusebius C. Onyeneke

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The purpose of the present study was to evaluate the effect of cadmium on some protein digestive and absorption enzymes in rats. Thirty-six rats were grouped into three groups of 12 animals each; one group received deionised water and acted as control. One group received 445 µM Cd and the last group received 890 µM Cd in their drinking water for a period of(More)
Lipid concentrations in human subjects during and after infection by Plasmodium falciparum were determined. The increase in the concentration of phospholipids and triglycerides during infection was statistically significant (p less than 0.01 for moderate infection and p less than 0.001 for severe infection) when compared with concentration after infection.(More)
In this study, attempt is made to establish changes in serum and liver lipoprotein cholesterols accompanying Plasmodium berghei malarial infection in mice treated with aqueous extract of Ganoderma lucidum at 100, 250, and 500 mg/kg body weight in comparison with 15 mg/kg chloroquine (CQ). Significant increases in all the lipoprotein fractions were observed(More)
Lipase (triacyglycerol acyl hydrolase, E. C. 3.1.1.3) activity was demonstrated on acetone powder prepared from coconut seeds, under different nutrients condition. Conversion of the free fatty acid released to copper salt enabled the activity of the crude enzyme extract on coconut oil, triolein, tripalmitine and olive oil to be determined colorimetrically.(More)
Long term administration of aspirin show efficacy in prevention of colon cancer and drug action is dependent on its interaction with nutrients. This study is aimed at assessing the role of the interaction between a Nigerian-like diet (NLD) or Western-like diet (WLD) and aspirin on energy metabolism and ATPases in early colon carcinogenesis. We observed that(More)
The serum protein levels were determined in 158 malarial patients infected with Plasmodium falciparum. Contrary to an earlier reported protein deficiency during malarial infection, the results obtained from this study showed no significant change (p > 0.05) in serum protein levels when compared with the controls. The significance of the results related to(More)
The fatty acids were studied of the total lipid extracts of mature liver flukes Fasciola gigantica from the bile ducts of Nigerian zebu cattle. The high content of saturated fatty acids, which amounted to more than 54% of the total fatty acids, conferred a high level of saturation on these parasites. This was brought about by a general increase in the(More)
Glucagon, dibutyryl cAMP (Bt2cAMP) and 8-(4-chlorophenylthio) cAMP (CptcAMP), singly or when combined, stimulated tyrosine aminotransferase (TAT) activity in 17-day-old chick embryos in ovo. Maximal induction was produced within 4 hr of injection of the inducers. The effects of glucagon and the cAMP analogues were not additive. Glucagon administration was(More)
Hematological and antioxidant effects of the aqueous extract of fruiting bodies of Ganoderma lucidum were evaluated in Plasmodium berghei-infected mice. Extract was administered at doses of 100, 250, and 500 mg/kg body weight by an intragastric tube once daily for 14 d starting from the fourth day after parasite inoculation. At the end of treatment period,(More)
The effect of soy protein on serum lipid profile and some lipid metabolizing enzymes in rats fed with cholesterol diets was examined in this study. Rats were subjected to feeding trial over a period of six weeks on formulated diets containing: 20% soy protein with 0% cholesterol (group A); 20% soy protein with 5% cholesterol (group B), 20% soy protein with(More)