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Revisions to the Classification, Nomenclature, and Diversity of Eukaryotes
TLDR
It is confirmed that eukaryotes form at least two domains, the loss of monophyly in the Excavata, robust support for the Haptista and Cryptista, and suggested primer sets for DNA sequences from environmental samples that are effective for each clade are provided. Expand
Evolutionary relationships of apusomonads inferred from taxon-rich analyses of 6 nuclear encoded genes.
TLDR
The data suggest that unikonts (=Opisthokonta and Amoebozoa) are not strictly monophyletic and are descended from biflagellate ancestors, rather than the current model that eukaryotes are divided into primary "unikent" and "bikont" clades. Expand
Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs
TLDR
The nuclear genomes of the cryptophyte Guillardia theta and the chlorarachniophyte Bigelowiella natans are sequenced and extensive genetic and biochemical mosaicism is revealed, with both host- and endosymbiont-derived genes servicing the mitochondrion, the host cell cytosol, the plastid and the remnant endosYmbionT cytOSol of both algae. Expand
TC1 (C8orf4) enhances the Wnt/beta-catenin pathway by relieving antagonistic activity of Chibby.
TLDR
It is shown that TC1 (C8orf4), a small protein present in vertebrates, functions as a positive regulator of the Wnt/beta-catenin pathway that enhances aggressive behavior of cancers. Expand
Intracellular invasion of green algae in a salamander host
TLDR
The invasion of algae into salamander host tissues and cells represents a unique association between a vertebrate and a eukaryotic alga, with implications for research into cell–cell recognition, possible exchange of metabolites or DNA, and potential congruence between host and symbiont population structures. Expand
Palpitomonas bilix represents a basal cryptist lineage: insight into the character evolution in Cryptista
TLDR
The taxonomic assignment of P. bilix, and character evolution in Cryptista is discussed, which was found to be basal to a clade of cryptophytes, goniomonads and kathablepharids collectively known as Cryptista, which is proposed to be a part of the larger taxonomic assemblage Hacrobia. Expand
EEF2 Analysis Challenges the Monophyly of Archaeplastida and Chromalveolata
TLDR
The authors' EEF2 analysis strongly refutes the monophyly of the Archaeplastida and the Chromalveolata, adding to a growing body of evidence that limits the utility of these supergroups. Expand
Phylogenetic Analysis of Algal Symbionts Associated with Four North American Amphibian Egg Masses
TLDR
Combined analysis shows that symbiotic algae found in egg masses of four North American amphibians are closely related to each other, and form a well-supported clade that also contains three strains of free-living chlamydomonads. Expand
Bacterial proteins pinpoint a single eukaryotic root
TLDR
The results firmly indicate that (i) the supergroup Excavata is not monophyletic and (ii) the last common ancestor of eukaryotes was a biflagellate organism. Expand
The CIL-1 PI 5-Phosphatase Localizes TRP Polycystins to Cilia and Activates Sperm in C. elegans
TLDR
The studies identify the CIL-1 5-phosphatase as a key regulator of PI metabolism in cell types that are important in several aspects of male reproductive biology. Expand
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