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  • Jenna L Jewell, Eunjin Oh, Sara M Bennett, Samy O. Meroueh, Debbie C Thurmond
  • Biology, Medicine
  • Journal of Biological Chemistry
  • 2008 (First Publication: 1 August 2008)
  • Glucose-stimulated insulin secretion is mediated by syntaxin 4-based SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) protein complexes and the Sec1/Munc18 proteinContinue Reading
  • Zhan-xiang Wang, Eunjin Oh, D. Wade Clapp, Jonathan Chernoff, Debbie C Thurmond
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 2011 (First Publication: 3 October 2011)
  • Background: P21-activated kinase (PAK1) is a downstream effector of the GTPase Cdc42. Results: Inhibition of Cdc42-PAK1 signaling in human islets inhibited insulin secretion. PAK1 knock-out miceContinue Reading