Trade-off between modularity and performance for engineered systems and products.
BACKGROUND Chronic respiratory failure complicating sleep-disordered breathing in obese patients has important adverse clinical implications in terms of morbidity, mortality and healthcare utilisation. Screening strategies are essential to identify obese patients with chronic respiratory failure. METHOD Prospective data were collected from patients with… (More)
BACKGROUND We compared indomethacin therapy with the more aggressive approaches of anti-cancer chemotherapy and surgery in the treatment of isolated Langerhans cell histiocytosis (LCH) of bone in children. METHODS Comparisons were made with respect to healing of the lesion without recurrence, time to radiological healing of the lesion, time to functional… (More)