Eun Myoung Shin

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Demethoxycurcumin and bisdemethoxycurcumin are the main active ingredients isolated from Curcumae Longae Radix. Recent studies demonstrated that both compounds exhibit antioxidative and anti-inflammatory effects as well as effects on cancer cell lines. In this study, we compared the activities of demethoxycurcumin and bisdemethoxycurcumin, and both(More)
Abbreviations: DP103, DEAD-box protein 103; MAPK, mitogen-activated protein kinase; MMP9, matrix metallopeptidase 9; NF-kB, nuclear factor kappa-light-chain-enhancer of activated B cells; PIASy, protein inhibitor of activated STAT protein gamma; SUMO, small ubiquitin-like modifier; TAK1, transforming growth factor b-activated kinase 1. DEAD-box protein-103(More)
Multiple myeloma (MM) is a malignant plasma cell tumor often arising in the bone marrow and is the most common non-Hodgkin’s haematological malignancy contributing 13 % of all malignancy and 1 % of neoplasia. MM arises from a pre-malignant condition known as ‘monoclonal gammapathy of undermined significance’. The aberrant antibodies that are produced leads(More)
Because aging and inflammation mechanisms share common signaling pathways and mediators, natural products with anti-inflammatory effects are also good candidates as anti-aging agents. Bismethoxycurcumin, demethoxycurcumin, and curcumin are three curcuminoids that can be isolated from Curcuma longa and are well known for their anti-inflammatory and(More)
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