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Zinc Activates TREK-2 Potassium Channel Activity
TLDR
Stimulation by Zn2+ may be used as a criterion of TREK-2, distinguishing it from other two-pore K+ channels. Expand
The transcription factor STAT2 enhances proteasomal degradation of RCAN1 through the ubiquitin E3 ligase FBW7.
TLDR
It is reported that RCAN1 interacts with the inflammation-linked transcription factor, signal transducer and activator of transcription 2 (STAT2) in mammalian cells, and co-immunoprecipitation/immunoblot analyses suggest that STAT2 influences diverse cellular processes linked toRCAN1 by negatively affecting RCAN 1 protein stability. Expand