Eugeny V Berdyshev

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Neurons (both primary cultures of 3-day rat hippocampal neurons and embryonic chick neurons) rapidly converted exogenous NBD-sphingomyelin (SM) to NBD-Cer but only slowly converted NBD-Cer to NBD-SM. This was confirmed by demonstrating low in vitro sphingomyelin synthase (SMS) and high sphingomyelinase (SMase) activity in neurons. Similar results were(More)
1. The relative content of 16:0, 17:0 and 18:0 fatty aldehydes in the lipids of eight species of the far-eastern Bryozoa was studied. 2. Heptadecanoic aldehyde is one of the main aldehydes in the seven species investigated comprising about 30% of the sum of these main bryozoan aldehydes. 3. We suggest the unusually high relative heptadecanoic aldehyde(More)
The effects of the platelet-activating factor (PAF) and the methoxy-PAF analog, 1-O-alkyl-2-methoxy-sn-glycero-3-phosphocholine, on platelet activation, oxidative burst in neutrophils and proliferation of K-562 and P815 cells have been studied. It has been found that the biological activity of methoxy-PAF for human platelets and neutrophils is commensurate(More)
O-acetylated sphingomyelin (Ac-SM) was found to cause aggregation of rabbit platelets in vitro. The Ac-SM-induced aggregation was accompanied by subsequent desensitisation of platelets to platelet-activating factor (PAF). The activity of Ac-SM exceeded that of acyl-PAF by about fourfold. BN 52021, a specific PAF-receptor antagonist, was found to inhibit the(More)
The composition of the lipids, fatty acids, and aldehydes of the hydroid “cross” medusaC. vertens has been investigated. It has been shown that the free sterols are the main components of the phospholipids of the medusa and 78% of them consists of cholesterol. Phosphatidylethanolamine is the main phospholipid of the medusa and 74.4% of it is represented by(More)
The aqueous solutions of 3 acidic and 14 basic dyes used as reagents for detection of lipids without their destruction are tested on plates for highly effective TLCh with the silicagel layer fixed by the silicic acid sol. It is shown that 0.002% solution of basic fuchsin in 1% boric acid reveals neutral, phospho- and glycolipids with the sensitivity(More)
The compositions of the fatty aldehydes from the phosphatidylethanolamines of 26 species of marine invertebrates belonging to nine classes of six types have been investigated. It has been shown that for the aldehydes of all the animals investigated a high degree of saturation and the presence of substantial amounts of branched aldehydes and aldehydes with(More)
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