Eugene S Vysotski

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The crystal structures of calcium-loaded apo-aequorin and apo-obelin have been determined at resolutions 1.7A and 2.2 A, respectively. A calcium ion is observed in each of the three EF-hand loops that have the canonical calcium-binding sequence, and each is coordinated in the characteristic pentagonal bipyramidal configuration. The calcium-loaded(More)
147 Further development of fundamental and applied research in the fields of biology, medicine, and pharr macology requires effective noninvasive technologies of realltime imaging of molecular processes both in a single cell and in the whole organism. Cloning of the gene encoding firefly luciferase marked the beginning of an intensive use of luciferases as(More)
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