Eugene Ozhinsky

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Micro-finite element (FE) analysis is a well established technique for the evaluation of the elastic properties of trabecular bone, but is limited in its application due to the large number of elements that it requires to represent the complex internal structure of the bone. In this paper, we present an alternative FE approach that makes use of a recently(More)
PURPOSE To quantify normal, in vivo tibio-femoral knee joint kinematics in multiple weight bearing positions using non-invasive, high-resolution MRI and discuss the potential of developing future kinematic methods to assess patients with abnormal joint pathologies. METHODS Ten volunteers with clinically normal knees pushed inferiorly on the footplate of a(More)
Noninvasive assessment of articular cartilage using magnetic resonance imaging (MRI) has gained popularity in the diagnosis of osteoarthritis (OA), a condition that affects 20 million Americans. Focal cartilage lesions, a defect found in roughly 19% of the OA population, currently can only be evaluated with confidence using minimally invasive arthroscopy.(More)
BACKGROUND The purpose of this study was to evaluate the feasibility of using a short echo time, three-dimensional H-1 magnetic resonance spectroscopic imaging (MRSI) sequence at 7 Tesla (T) to assess the metabolic signature of lesions for patients with glioma. METHODS Twenty-nine patients with glioma were studied. MRSI data were obtained using CHESS(More)
BACKGROUND Previous studies of the patellofemoral joint have been limited by the use of invasive techniques, measurements under non-weight-bearing conditions, cadaveric specimens, or computerized models. It has been shown that soft tissue and bone can be accurately quantified with magnetic resonance imaging. The present study was designed to define the(More)
PURPOSE To compare the precision and accuracy of 3.0-T and 1.5-T magnetic resonance (MR) imaging in the quantification of cartilage volume by using direct volumetric measurements as a reference standard. MATERIALS AND METHODS The local animal experimentation committee did not require its approval for this study. Porcine knees were obtained from an(More)
J. Carballido-Gamio, K. Lee, E. Ozhinsky, S. Majumdar University of California, San Francisco, San Francisco, California, United States Introduction. A common manifestation of osteoarthritis (OA) of the knee is the morphological degeneration of articular cartilage. Magnetic resonance imaging (MRI) offers the potential to visualize and analyze quantitatively(More)
PURPOSE To develop a technique for optimizing coverage of brain 3D (1) H magnetic resonance spectroscopic imaging (MRSI) by automatic placement of outer-volume suppression (OVS) saturation bands (sat bands) and to compare the performance for point-resolved spectroscopic sequence (PRESS) MRSI protocols with manual and automatic placement of sat bands. (More)
In vivo MRSI is an important imaging modality that has been shown in numerous research studies to give biologically relevant information for assessing the underlying mechanisms of disease and for monitoring response to therapy. The increasing availability of high field scanners and multichannel radiofrequency coils has provided the opportunity to acquire in(More)
Two major difficulties encountered in implementing Magnetic Resonance Spectroscopic Imaging (MRSI) in a clinical setting are limited coverage and difficulty in prescription. The goal of this project was to automate completely the process of 3D PRESS MRSI prescription, including placement of the selection box, saturation bands and shim volume, while(More)