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OBJECTIVE To test whether the serial measurement of maternal levels of compound W, a 3,3'-diiodothyronine sulfate cross-reactive substance, can serve as a potential indicator of fetal thyroid function in pregnant women receiving antithyroid medication. METHODS Compound W was measured repeatedly in serum of pregnant women with hyperthyroidism treated with(More)
We used novel 3'-monoiodothyronine sulfate (3'-T1S) and 3,3',5-triiodothyroacetic acid sulfate (TriacS) RIAs to characterize sulfation pathways in fetal thyroid hormone metabolism. 3'-T1S and TriacS levels were measured in serum samples obtained from fetal (n = 21, 94-145 d gestational age), newborn (NB, n = 5), and adult sheep (AD, n = 5) as well as from(More)
Compound W, a 3,3'-diiodothyronine sulfate (T2S) cross-reactive material in maternal serum, was found to be useful as a marker for fetal hypothyroidism. In the present report, we explored its biochemical properties and studied its concentrations in cord and in maternal serum obtained from various gestational periods and at term from different continents.(More)
Like many malignancies, increased glucose uptake is also found in activated inflammatory cells that raise great interest in the applications of FDG in evaluating inflammatory and infectious disorders. 18 F-FDG has been shown to accumulate in inflamed tissue including autoimmune induced vasculitis and inflamed athero-sclerotic lesions. Advantages of FDG(More)
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