Eugene Antipov

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A bio-based economy has the potential to provide sustainable substitutes for petroleum-based products and new chemical building blocks for advanced materials. We previously engineered Saccharomyces cerevisiae for industrial production of the isoprenoid artemisinic acid for use in antimalarial treatments. Adapting these strains for biosynthesis of other(More)
Aspects of Evolutionary Computation, DNA computing, and in vitro evolution are combined in proposed laboratory procedures. Preliminary experimental results are shown. The traditional test problem for Evolutionary Computation known as the OneMax problem is addressed. The preliminary experimental results indicate successful laboratory separation by tness" of(More)
Genetic algorithms, DNA computing, and in vitro evolution are brieey discussed. Elements of these are combined into laboratory procedures, and preliminary results are shown. The traditional test problem for genetic algorithms called the MAX 1s problem is addressed. Preliminary experimental results indicate successful laboratory separation by tness" of DNA(More)
Isoprenoids are used in many commercial applications and much work has gone into engineering microbial hosts for their production. Isoprenoids are produced either from acetyl-CoA via the mevalonate pathway or from pyruvate and glyceraldehyde 3-phosphate via the 1-deoxy-D-xylulose 5-phosphate (DXP) pathway. Saccharomyces cerevisiae exclusively utilizes the(More)
Topics This panel discussion will attempt to clarify the outstanding unresolved issues in DNA computing. A brief and incomplete list of concerns is given below. 1. What are the accomplishments in DNA computing to date? 2. What are the problems for which DNA based computing is the preferred solution method? 3. Can laboratory techniques be found or modiied to(More)
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