Eugene Antipov

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A bio-based economy has the potential to provide sustainable substitutes for petroleum-based products and new chemical building blocks for advanced materials. We previously engineered Saccharomyces cerevisiae for industrial production of the isoprenoid artemisinic acid for use in antimalarial treatments. Adapting these strains for biosynthesis of other(More)
Genetic algorithms, DNA computing, and in vitro evolution are brie y discussed. Elements of these are combined into laboratory procedures, and preliminary results are shown. The traditional test problem for genetic algorithms called the MAX 1s problem is addressed. Preliminary experimental results indicate successful laboratory \separation by tness" of DNA(More)
Aspects of Evolutionary Computation, DNA computing, and in vitro evolution are combined in proposed laboratory procedures. Preliminary experimental results are shown. The traditional test problem for Evolutionary Computation known as the OneMax problem is addressed. The preliminary experimental results indicate successful laboratory \separation by tness" of(More)
Isoprenoids are used in many commercial applications and much work has gone into engineering microbial hosts for their production. Isoprenoids are produced either from acetyl-CoA via the mevalonate pathway or from pyruvate and glyceraldehyde 3-phosphate via the 1-deoxy-D-xylulose 5-phosphate (DXP) pathway. Saccharomyces cerevisiae exclusively utilizes the(More)
[2] Thomas Back, Joost N. Kok, and Grzegorz Rozenberg. Evolutionary computation as a paradigm for DNA-based computing. In Laura Landweber, Erik Winfree, Richard Lipton, and Stephan Freeland, editors, Preliminary Proceedings DIMACS Workshop on Evolution as Computation, pages 67{88, DIMACS, Piscataway NJ, January 1999. Available on request from DIMACS. Paper(More)
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