Etienne Grau

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The HNF-3 alpha, beta and gamma genes constitute a family of transcription factors that are required for hepatocyte-specific gene expression of a number of genes, e.g. transthyretin, alpha-1 antitrypsin and tyrosine aminotransferase. These genes share a highly conserved DNA-binding domain first found in the Drosophila gene, forkhead, which is required for(More)
The Drosophila tailless gene is a member of the orphan nuclear receptor subfamily. In Drosophila, the tailless gene is required for pattern formation in embryonic poles. During development, tailless is activated in the termini of the embryo in response to the torso receptor tyrosine kinase signal transduction cascade. Recessive mutations of tailless result(More)
Endocrine disruptors exert physiological effects at very low concentrations. Surface waters present often a mixture of high concentrations of low-potency disruptors and low amounts of very powerful ones, making their chemical analysis complicated and expensive. We developed a recombinant yeast assay (RYA) for estrogenic compounds using 96-well microtiter(More)
PURPOSE Inherited retinal dystrophies and hearing loss disorders have a broad clinical and genetic heterogeneity. Over the last decade there have been major advances in our understanding of the molecular pathology of these diseases; currently over 200 genes and loci are known to be involved in retinal disorders, and over 60 genes/loci are causative for(More)
This work provides an evaluation of the Discrete Anisotropy Radiative Transfer (DART) 3-dimensional model to assess the simulation of directional brightness temperatures both at-sensor and at-surface levels. Satellite imagery acquired with the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER), airborne imagery acquired with the Airborne(More)
Free radical polymerization of ethylene in an intermediate pressure and temperature range (P(ethylene) < 250 bar and 50 °C < T < 90 °C) in the presence of an organic solvent has been studied. Under selected conditions (P, T) and according to the amount of organic solvent added, either a supercritical monophasic or a biphasic medium is obtained. In the case(More)