Estrella Alvarez

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BACKGROUND Hypercholesterolaemia is a risk factor for coronary heart disease (CHD). Clinical studies have shown that lowering elevated serum total cholesterol (TC) levels, and particularly low density lipoprotein-cholesterol (LDL-C) levels, reduces the frequency of coronary morbidity and deaths, whereas high serum levels of high density(More)
Ultra-high molecular weight polyethylene (UHMWPE) is a common bearing component in total knee replacement (TKR) implants, and its susceptibility to wear continues to be the long-term limiting factor in the life of these implants. This study hypothesized that in TKR systems, a highly cross-linked (HXL) UHMWPE blended with vitamin E will result in reduced(More)
OBJECTIVE To investigate the effects of D-003 on the bleeding time (BT) and lipid profile of healthy human volunteers. METHODS This single-blind, randomised, placebo-controlled, parallel-group study was conducted in healthy volunteers. Step 1 investigated the effects of single doses of D-003 5, 25 or 50 mg on BT in comparison with placebo. Step 2(More)
INTRODUCTION Bubble columns are widely used in industrial gas-liquid operations (e.g. gas-liquid reactions , fermentations) in chemical and biochemical processes industries, due to their simple construction, low operating cost and high-energy efficiency. In all these processes, gas holdup and bubble size are important design parameters since they define the(More)
Determination of interfacial areas in absorption processes have been experimentally investigated in a bubble column using a physical method (photographic method) and a chemical method (Danckwerts´method). Experiments were conducted in a vertical column 11.3 cm in diameter and 108.6 cm in height. The range of variables used is common for both methods. All(More)
A bubble column was used to study the heat effect on CO 2 absorption in methydiethanolamine solutions and on volumetric mass transfer coefficient. It was found that the temperature varied until 4 ºC between the beginning and the end of the process. Our studies provide an empirical correlation type Boltzmann to estimate the temperature at different amine(More)
Oculokinetic perimetry is a new method of visual field assessment in which the patient moves the eye around a central static target to look sequentially at an array of numbers. When fixation on a number is accompanied by disappearance of the central target, that number is deleted from a recording chart. Inversion of the recording chart gives a plot of the(More)
The volumetric mass transfer coefficients at different axial positions in a bubble column were measured using a conductivity method. The absorption process of CO 2 in monoethanolamine solutions was carried out in a prismatic column 0.06 m side and 1.03 m height. Measurements were conducted at various gas flow rates and amine concentration. The local mass(More)
BACKGROUND Policosanol is a drug derived from sugar cane wax that has cholesterol-lowering and antiplatelet properties. Randomized, controlled studies are the gold standard for demonstrating drug efficacy, safety, and tolerability, but postmarketing surveillance studies are encouraged for corroborating drug effects. A valid proof of the safety of a drug is(More)
A control system based on a combination of the gain-scheduling control method and an adaptive PID controller was designed for the production of xylose from hardwood hemicellulose using a stirring tank reactor. Different operating conditions have been considered for estimating the adjustable parameter (theta) to take into account the changes of energy of the(More)
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