Esther van 't Riet

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OBJECTIVE To investigate the relationship among A1C, fasting plasma glucose (FPG), and 2-h postload plasma glucose in the Dutch general population and to evaluate the results of using A1C for screening and diagnosis of diabetes. RESEARCH DESIGN AND METHODS In 2006-2007, 2,753 participants of the New Hoorn Study, aged 40-65 years, who were randomly(More)
BACKGROUND Genome-wide association studies in Japanese populations recently identified common variants in the KCNQ1 gene to be associated with type 2 diabetes. We examined the association of these variants within KCNQ1 with type 2 diabetes in a Dutch population, investigated their effects on insulin secretion and metabolic traits and on the risk of(More)
AIMS To investigate the associations of HbA1c, fasting glucose, and postload plasma glucose with 10-year fatal and non-fatal cardiovascular disease (CVD) and all-cause mortality in Caucasian individuals between 50 and 75 years of age without diabetes. METHOD AND RESULTS The 10-year risk of all-cause mortality and CVD in relation to HbA1cand glucose levels(More)
BACKGROUND Good clinical results have been reported for both surgical and conservative treatment of rotator cuff tears. The primary aim of this randomized controlled trial was to compare functional and radiologic improvement after surgical and conservative treatment of degenerative rotator cuff tears. METHODS We conducted a randomized controlled trial(More)
OBJECTIVE To investigate whether the anti-emetics metoclopramide and domperidone can be replaced by 5-HT3-antagonists, as side effects restrict use of these dopamine antagonists. DESIGN Systematic review. METHOD We searched the Embase and PubMed databases for articles published in the period 1995-October 2015, in which the efficacy or side effects of(More)
Psychological problems are common in shoulder patients. A validated psychological questionnaire measuring clinically relevant psychological symptoms (including distress, depression, anxiety, and somatization) in shoulder patients is lacking. The Four-Dimensional Symptom Questionnaire (4DSQ) is a self-report questionnaire to identify distress, depression,(More)
Overweight (BMI level > or =25 kg/m2) and in particular high abdominal fat levels (waist circumference > or =88 cm in women and > or =102 cm in men), are among the main risk factors for the development of type 2 diabetes mellitus. Results from the Hoorn Study show that 16.3% of overweight participants with high abdominal fat levels developed diabetes within(More)
OBJECTIVE To evaluate to what extent the association between family history of diabetes and risk of type 2 diabetes can be explained by excess adiposity and lifestyle risk factors. RESEARCH DESIGN AND METHODS We analyzed data from 73,227 women who participated in the Nurses' Health Study cohort. A family history of diabetes was defined as having at least(More)
AIMS Modulation of dopamine receptor D2 (DRD2) activity affects insulin secretion in both rodents and isolated pancreatic β-cells. We hypothesized that single nucleotide polymorphisms in the DRD2/ANKK1 locus may affect susceptibility to type 2 diabetes in humans. METHODS Four potentially functional variants in the coding region of the DRD2/ANKK1 locus(More)
INTRODUCTION Many patients with intentional drug overdose (IDO) are admitted to a medium (MC) or intensive care unit (IC) without ever requiring MC/IC related interventions. The objective of this study was to develop a decision tool, using parameters readily available in the emergency room (ER) for patients with an IDO, to identify patients requiring(More)