Esteban Schabelman

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Pigment epithelial-derived factor (PEDF) has been shown to be a survival factor for cerebellar granule neurons. Here we investigated the ability of PEDF to enhance the survival of hippocampal neurons in culture, and to protect these neurons against acute glutamate toxicity. Hippocampal neurons prepared from 1- to 3-day postnatal rat brain were cultured for(More)
BACKGROUND Radiocontrast agents are some of the most commonly used medications in the emergency department. However, both physicians and patients misunderstand the role that allergies play in reactions to radiocontrast media, especially with regards to shellfish and iodine. OBJECTIVES We sought to review the literature describing rates of contrast(More)
BACKGROUND The prevailing teaching in medical school curricula and in medical textbooks is that if thiamine deficiency is suspected, thiamine supplementation should be given before administering glucose. OBJECTIVE We sought to evaluate the published evidence describing the commonly held belief that thiamine supplementation must be given before glucose in(More)
BACKGROUND The practice of avoiding cephalosporin administration to penicillin-allergic patients persists despite the low rate of cross reactions between both groups of antibiotics. OBJECTIVE The purpose of this literature review is to evaluate the published evidence regarding the commonly held belief that patients with a history of an allergic reaction(More)
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