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  • Armin Hatzelmann, Esteban Jesús Morcillo, +5 authors Hermann Tenor
  • Medicine
  • Pulmonary pharmacology & therapeutics
  • 2010 (First Publication: 1 August 2010)
  • After more than two decades of research into phosphodiesterase 4 (PDE4) inhibitors, roflumilast (3-cyclopropylmethoxy-4-difluoromethoxy-N-[3,5-di-chloropyrid-4-yl]-benzamide) may become the firstExpand
  • Amadeu Gavaldá, Montserrat Miralpeix, +13 authors Jorge Beleta
  • Chemistry, Medicine
  • Journal of Pharmacology and Experimental…
  • 2009 (First Publication: 1 November 2009)
  • Aclidinium bromide is a novel potent, long-acting inhaled muscarinic antagonist in development for the treatment of chronic obstructive pulmonary disease. Aclidinium showed subnanomolar affinity forExpand
  • Manuel Mata, Benjamín Sarriá, Amparo Buenestado, Julio Cortijo, Martín Cerda, Esteban Jesús Morcillo
  • Medicine
  • Thorax
  • 2005 (First Publication: 28 January 2005)
  • Background: A common pathological feature of chronic inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease (COPD) is mucus hypersecretion. MUC5AC is the predominantExpand
  • Amparo Buenestado, Julio Cortijo, +6 authors Esteban Jesús Morcillo
  • Biology, Medicine
  • JPEN. Journal of parenteral and enteral nutrition
  • 2006 (First Publication: 1 July 2006)
  • BACKGROUND Infection remains a drawback of parenteral nutrition (PN), probably related, among other factors, to immunosuppressive effects of its lipid component. Newer preparations may have lesserExpand
  • Manuel Mata, Esteban Jesús Morcillo, Concepción Gimeno, Julio Cortijo
  • Biology, Medicine
  • Biochemical pharmacology
  • 2011 (First Publication: 1 September 2011)
  • 64% of chronic obstructive pulmonary disease (COPD) exacerbations are caused by respiratory infections including influenza (strains A and B) and respiratory syncytial virus (RSV). They affect theExpand