Erwin W. M. Roex

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The effect of the polychlorinated biphenyl (PCB) mixture Clophen A50 on hepatic cytochrome P4501A1 dependent EROD (7-ethoxyresorufin-O-deethylase) activity, plasma thyroid hormone levels and plasma, kidney and liver retinoid concentrations of the euryhaline flatfish flounder (Platichthys flesus) was determined 2 and 10 days after i.p. (intraperitoneal)(More)
The sensitivity of the early life stage (ELS) toxicity test for two compounds with different modes of action was determined, and related to other toxicity tests with the same compounds. The zebrafish. Danio rerio, was used as a test organism, and the two model compounds were 1,2,3-trichlorobenzene (123TCB), a non-polar narcotic, and parathion, an(More)
Global change, in particular climate change, will affect agriculture worldwide in many ways: increased drought or flooding amplitude and frequency, variable temperature increases, loss of natural depuration of waters, soil erosion, loss of soil carbon content, invasion by alien species, increased pest events, changes in plant phenology, increased(More)
Acetylcholinesterase (AChE) inhibition is widely regarded as a good biomarker of exposure to organophosphorus pesticides (OP). However, less is known about the relationship between AChE inhibition and consequences for growth, reproduction and survival on organisms. Acute toxicity tests with fish have shown that high percentages of AChE inhibition are needed(More)
The factors determining the bioaccumulation of lipophilic compounds in wildlife are often poorly understood, partly because it is difficult to do in vivo experiments with animals such as marine mammals and birds. To evaluate the role of phase I biotransformation in the bioaccumulation process of chlorobornanes (toxaphene), this was studied in in vitro(More)
Most organic pollutants are supposed to act via the mechanism of nonpolar narcosis upon acute exposure. Because the chronic effects of these compounds are still relatively unknown, in this study a chronic toxicity experiment was performed with zebrafish, Danio rerio, exposed to 1,2,3-trichlorobenzene (123TCB), a nonpolar narcotic. Fish were exposed in a(More)
Although nanoparticles are being increasingly used in consumer products, the risks they may pose to the environment and to human health remain largely unknown. One important reason for this is the lack of quantitative techniques for identifying and measuring the amount of nanomaterials in environmentally relevant circumstances. Such techniques should also(More)
As engineered nanoparticles of zinc oxide, titanium dioxide and silver, are increasingly used in consumer products, they will most probably enter the natural environment via wastewater, atmospheric deposition and other routes. The aim of this study is to predict the concentrations of these nanoparticles via wastewater emissions in a typical river system by(More)
With nanoparticles being used more and more in consumer and industrial products it is almost inevitable that they will be released into the aquatic environment. In order to understand the possible environmental risks it is important to understand their behavior in the aquatic environment. From laboratory studies it is known that nanoparticles in the aquatic(More)