Eronique Bernard

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Four cardiotoxins (CTX I-IV) from Naja mossambica mossambica were compared for their ability to interact with phospholipid vesicles and their capacity to bind erythrocytes. It is concluded that the affinity of the toxins always increases in the order: I approximately equal to II less than III less than IV. The binding is specific for charged lipids even in(More)
Interactions between melittin and a variety of negatively-charged lipid bilayers have been investigated by intrinsic fluorescence, fluorescence polarization of 1,6-diphenylhexatriene and differential scanning calorimetry. (1) Intrinsic fluorescence of the single tryptophan residue of melittin shows that binding of this peptide to negatively-charged(More)
Nuclear forces can be systematically analyzed in the framework of chiral effective field theory (EFT). The starting point is a chiral Lagrangian of pions, nucleons and external sources, like e.g. photons. At low energies, one can expand S–matrix elements and transition currents in powers of small external momenta/energies and the light quark masses. In case(More)
Vascular malformations are infrequent findings in the foot, especially the plantar medial foot. Deeper vascular malformations may be more difficult to diagnose due to the depth and oblique course of the medial neurovascular structures into plantar aspect of the foot. The authors present an interesting case report of a vascular anomaly mimicking a heel spur(More)
The effects of a Naja mossambica mossambica cardiotoxin on the thermotropic properties of charged phospholipids have been studied by fluorescence polarization, differential scanning calorimetry, and Raman spectroscopy. The binding of the toxin is only governed by the net charge at the interface and is not affected by the polar head group structure of the(More)
The binding of melittin to phospholipid bilayers and micelles depends on its quaternary structure and on the state of association of lipids. Monomeric melittin only binds to lipids above their cmc, whereas tetrameric melittin exhibits a biphasic binding; the interaction with monomeric lipids being possible without dissociation of the tetramer. In lipid(More)
Recordings were made from neurons in the dorsal horn (DH), and from dorsal and ventral roots (DRs and VRs) of isolated spinal cords of infant mice. Raising calcium concentration ([Ca2+]) in the organ bath from 1.2 to 2.4 mmol/l resulted in a slight hyperpolarization, elevation of threshold current (rheobase), and augmentation of excitatory postsynaptic(More)