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—A 12 bit 2.9 GS/s current-steering DAC implemented in 65 nm CMOS is presented, with an 3 60 dBc beyond 1 GHz while driving a 50 load with an output swing of 2.5 ppd and dissipating a power of 188 mW. The SFDR measured at 2.9 GS/s is better than 60 dB beyond 340 MHz while the SFDR measured at 1.6 GS/s is better than 60 dB beyond 440 MHz. The increase in(More)
Since the recent publication of the World Health Organization brain tumour classification guidelines in 2007, a significant expansion in the molecular understanding of glioblastoma multiforme (GBM) and its pathological as well as genomic variants has been evident. The purpose of this review article is to evaluate the histopathological, molecular and(More)
BACKGROUND Chronic kidney disease (CKD) is associated with increased risk for cardiovascular (CV) disease and is also associated with elevated uric acid, which is emerging as a nontraditional CV risk factor. We therefore evaluated uric acid as a risk factor for CV disease in subjects presenting to nephrologists with CKD who were not on medications known to(More)
BACKGROUND Polycystic ovary syndrome (PCOS) is one of the most common endocrinopathies. Chronic infections may increase the risk of infertility. Helicobacter pylori infection has been found to be associated with infertility, and PCOS is also one of the most common causes of infertility. To the best of our knowledge, the possible association between H.(More)
Glioblastoma multiforme (GBM) is an aggressive grade IV astrocytoma with a 1-year median survival rate despite current treatment modalities. A thorough understanding of the vast genetic aberrations and signaling pathways involved in gliomagenesis as well as heterogeneous clinicopathological presentation remains elusive. The recent discovery of microRNAs(More)
BACKGROUND Obesity and Helicobacter pylori (H. pylori) are important because of the problems they lead and their frequency of occurrence. In this study, we aimed to find out the prevalence of H. pylori infection and the relationship between obesity and H. pylori in obese and normal weight subjects. METHODS A total of 214 subjects were (103 obese (71 male,(More)
Neutrophils and lymphocytes (N/L) ratio and carotid intima-media thickness (C-IMT) value have been studied as new predictors of cardiovascular risk. We aimed to investigate N/L ratio and C-IMT value in patients with cardiac syndrome X (CSX) and compare patients with coronary artery disease (CAD) and normal participants. A total of 288 participants were(More)
BACKGROUND Endothelial nitric oxide synthase produces nitric oxide which is involved in many physiologic regulatory functions. Variable number of tandem repeats in intron 4 of endothelial nitric oxide synthase gene are reported to be associated with blood pressure regulation. Nitric oxide is involved in regulation of cardiomyocyte genes but it is not known(More)
BACKGROUND AND AIMS In our detailed analysis of the recent academic publications, we have not found sufficient evidence regarding the changes of metabolism that occur in cases of insulin resistance (IR) and nonalcoholic fatty liver disease (NAFLD). We aimed to investigate the changes in various biomarkers of obese patients by taking into consideration the(More)