Ernst-Ulrich Griese

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BACKGROUND Previously, we have demonstrated a marked inhibition of codeine glucuronidation by diclofenac in human liver tissue homogenate. We therefore aimed to investigate whether diclofenac inhibits glucuronidation of codeine also in vivo in healthy volunteers. METHODS In a randomised, placebo-controlled, double-blind, cross-over study, 12 healthy(More)
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