Ernesto de Menis

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Acromegalic patients have a higher risk of developing colorectal tumours (CRT). The common C677T polymorphism in methylenetetrahydrofolate reductase (MTHFR) gene is a well-documented CRT risk factor in the general population, but its role in acromegaly has never been examined. We investigated the influence of MTHFR C677T polymorphism, folate status and(More)
Hyperprolactinemia may cause bone loss but data on fractures are scanty. The aim of this study was to evaluate the prevalence of vertebral fractures in women with prolactin (PRL)-secreting adenoma. In this cross-sectional study, 78 women (median age 45.5 years, range: 20–81) with PRL-secreting pituitary adenoma (66 with microadenoma and 12 with(More)
Amar Agha Faisal Ahmed Gianluca Aimaretti Fulya Akin Keya Ali Bruno Allolio Olaf Ansorge Baha Arafah Emanuela Arvat Simon Aylwin John Ayuk Stephanie Baldeweg A. Beckers Gary Bell Anat Ben-Shlomo Rita Berardelli John Bevan Antonio Bianchi Nienke Biermasz Jens Bollerslev V. Bonert Marco Boscaro Karin Bradley Marcello Bronstein Antonia Brooke Michael(More)
Serum #2-microglobulin concentrations were determined in 21 untreated hyper-thyroid patients (12 with Graves' disease, and nine with toxic nodular adenoma) and in 20 healthy controls. All subjects had normal serum creatinine concentrations and urine analysis. Both total and free thyroid hormones were significantly higher in the hyperthyroid groups than in(More)
Acute onset of primary hyperparathyroidism is uncommon; neuropsychiatric signs are prominent clinical features in acute hypercalcemia and they can subside after normalization of serum calcium. Radiation therapy is a well-known risk factor for non medullary thyroid cancer, but it induces also parathyroid tumors. Data from the literature show that patients(More)
Isolated familial somatotropinomas (IFS) rarely occurs in the absence of multiple endocrine neoplasia type I (MEN1) or the Carney complex. In the present study we report two Italian siblings affected by GH-secreting adenomas. There was no history of parental consanguinity. The sister presented at 18 years of age with secondary amenorrhea and acromegalic(More)
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