Ernesto Casciaro

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Sergio Casciaro37
Francesco Conversano36
Roberto Franchini16
Christian Demitri14
Alessandro Distante13
31Francesco Conversano
31Sergio Casciaro
15Aimé Lay-Ekuakille
12Giulia Soloperto
12Antonio Greco

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Full experimental modelling of a liver tissue mimicking phantom for medical ultrasound studies employing different hydrogels.
Tissue mimicking phantoms have been widely reported to be an important tool for development, optimisation and performance testing of ultrasound-based diagnostic techniques. In particular, modern applications of tissue mimicking phantoms often include characterisation of the nonlinear behaviour of experimental ultrasound contrast agents. In such cases, the… (More)
Advanced spectral analyses for real-time automatic echographic tissue-typing of simulated tumor masses at different compression stages.
Prototypal software algorithms for advanced spectral analysis of echographic images were developed to perform automatic detection of simulated tumor masses at two different pathological stages. Previously published works documented the possibility of characterizing macroscopic variation of mechanical properties of tissues through elastographic techniques,… (More)
Sonographic markers for early diagnosis of fetal malformations.
Fetal malformations are very frequent in industrialized countries. Although advanced maternal age may affect pregnancy outcome adversely, 80%-90% of fetal malformations occur in the absence of a specific risk factor for parents. The only effective approach for prenatal screening is currently represented by an ultrasound scan. However, ultrasound methods… (More)
Screening and early diagnosis of osteoporosis through X-ray and ultrasound based techniques.
Effective prevention and management of osteoporosis would require suitable methods for population screenings and early diagnosis. Current clinically-available diagnostic methods are mainly based on the use of either X-rays or ultrasound (US). All X-ray based methods provide a measure of bone mineral density (BMD), but it has been demonstrated that other… (More)
Major osteoporotic fragility fractures: Risk factor updates and societal impact.
Osteoporosis is a silent disease without any evidence of disease until a fracture occurs. Approximately 200 million people in the world are affected by osteoporosis and 8.9 million fractures occur each year worldwide. Fractures of the hip are a major public health burden, by means of both social cost and health condition of the elderly because these… (More)
[Massive lower gastrointestinal bleeding due to diverticular disease during antiplatelet therapy. Case report].
Diverticular disease is very frequent in Western countries; in 5% of the cases it is the cause of serious bleeding, haemodynamic instability and death. The authors report a case of 74 years old patient with severe lower gastrointestinal bleeding. She was in antiplatelet treatment with acetylsalicylic acid (100 mg/die) and clopidogrel (75 mg/die) for… (More)
Fully automatic 3D segmentation measurements of human liver vessels from contrast-enhanced CT
Aim of the present work was to evaluate the performance of a novel fully automatic algorithm for 3D segmentation and volumetric reconstruction of liver vessel network from contrast-enhanced computed tomography (CECT) datasets acquired during routine clinical activity. Three anonymized CECT datasets were randomly collected and were automatically analyzed by… (More)
Echographic detectability of optoacoustic signals from low-concentration PEG-coated gold nanorods
PURPOSE To evaluate the diagnostic performance of gold nanorod (GNR)-enhanced optoacoustic imaging employing a conventional echographic device and to determine the most effective operative configuration in order to assure optoacoustic effectiveness, nanoparticle stability, and imaging procedure safety. METHODS The most suitable laser parameters were… (More)
Experimental investigation and theoretical modelling of the nonlinear acoustical behaviour of a liver tissue and comparison with a tissue mimicking hydrogel.
Native harmonics generated by nonlinear distortion of ultrasound during propagation in a medium may cause misinterpretations in spectral analysis when studying contrast agents. The aim of this paper is to quantitatively evaluate nonlinear propagation effects of diagnostic ultrasound pulses in biological tissues and to assess whether a cellulose-based… (More)