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In this paper we begin to investigate how to <i>automatically</i> determine the subjectivity orientation of questions posted by real users in community question answering (CQA) portals. Subjective questions seek answers containing private states, such as personal opinion and experience. In contrast, objective questions request objective, verifiable(More)
This work describes our experiences on discovering association rules in medical data to predict heart disease. We focus on two aspects in this work: mapping medical data to a transaction format suitable for mining association rules and identifying useful constraints. Based on these aspects we introduce an improved algorithm to discover constrained(More)
OBJECTIVES The purpose of this study is to assess mIBG uptake in scar border zone and its relation with ventricular arrhythmia (VA) inducibility on electrophysiology (EP) testing using I-123 mIBG SPECT and resting Tc-99m SPECT myocardial perfusion imaging (MPI). METHODS Forty-seven patients from a previous clinical trial were retrospectively analyzed.(More)
BACKGROUND We set out to develop normal databases and prospectively validate abnormality criteria for a low-dose Tc-99m tetrofosmin myocardial perfusion SPECT protocol using the 530c CZT camera. METHODS All patients received 6 mCi rest/20 mCi stress doses of Tc-99m tetrofosmin. Rest and stress images were obtained over 7-9 and 5-7 minutes according to the(More)
BACKGROUND The purpose of this study was to develop and validate new approaches to quantitative MIBG myocardial SPECT imaging in heart failure (HF) subjects. METHODS AND RESULTS Quantitative MIBG myocardial SPECT analysis methods, alone and in conjunction with 99mTc-tetrofosmin perfusion SPECT, were adapted from previously validated techniques for the(More)
NLM's Unified Medical Language System (UMLS) is a very large ontology of biomedical and health data. In order to be used effectively for knowledge processing, it needs to be customized to a specific domain. In this paper, we present techniques to automatically discover domain-specific concepts, discover relationships between these concepts, build a context(More)
BACKGROUND We evaluated the incremental diagnostic value of fusion images of coronary computed tomography angiography (CTA) and myocardial perfusion imaging (MPI) over MPI alone or MPI and CTA side-by-side to identify obstructive coronary artery disease (CAD > 50% stenosis) using invasive coronary angiography (ICA) as the gold standard. METHODS 50(More)
The current paper details the recommendations arising from an NIH-NHLBI/NCI-sponsored symposium held in November 2012, aiming to identify key components of a radiation accountability framework fostering patient-centered imaging and shared decision-making in cardiac imaging. Symposium participants, working in 3 tracks, identified key components of a(More)