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The aim of this study was to investigate the relation between reversible thallium single-photon emission computed tomography (SPECT) myocardial perfusion defects at 1-year after revascularization and quantitative indexes in Emory Angioplasty versus Surgery Trial (EAST) and outcomes 3 years after revascularization in 336 patients. EAST was a randomized(More)
BACKGROUND To determine the interpretability of gated thallium-201 perfusion SPECT compared with that performed by use of technetium-99m sestamibi (MIBI), 33 patients with prior myocardial infarction were studied. Patients received 22 to 30 mCi (814 to 1110 MBq) MIBI at peak stress, and a 15-minute gated SPECT acquisition was begun 30 to 40 minutes(More)
UNLABELLED A new technique for computing left ventricular function, including left ventricular volumes, mass and ejection fraction, has been developed. This method is a logical extension of the results of a standard perfusion quantification technique; thus, it allows integration of perfusion and functional information. METHODS Anatomically based models of(More)
By means of ECG gating of tomographic (SPECT) 99mTc-sestamibi (MIBI) images, myocardial perfusion and wall thickening have been evaluated after a single tracer injection. To determine if left ventricular ejection fraction (LVEF) can also be measured from gated MIBI SPECT, 30 patients 1 wk to 6 mo after myocardial infarction (MI) received 22-30 mCi(More)
OBJECTIVES This prospective study was conducted in 115 women to directly compare the sensitivity and specificity of thallium-201 (Tl-201), technetium-99m (Tc-99m) sestamibi perfusion and Tc-99m sestamibi electrocardiographic (ECG)-gated single-photon emission computed tomographic (SPECT) studies for detection of coronary artery disease (CAD). BACKGROUND(More)
  • E G DePuey
  • 1994
Although myocardial perfusion imaging with SPECT is an accurate and reliable diagnostic study, artifacts must be avoided, or detected and corrected, to minimize the rate of false-positive results. Common sources of artifacts are nonuniformity in gamma camera detectors, center of rotation errors, misaligned cameras on multidetector scanner systems, errors in(More)
Bone density begins to decline in women before menopause, and the degree of bone loss is variable. We performed a cross-sectional analysis on the entry data of a 5-yr prospective study of risk factors for osteoporosis to determine the correlation of bone density with serum sex steroid concentrations and body weight. We studied 292 healthy white women, aged(More)
The purpose of this study was to develop and validate a method for quantifying the uptake, redistribution, and washout of thallium-201 (201Tl) obtained with rotational tomography. This method generates maximum count circumferential profiles of the short-axis slices of the left ventricle, translates them into polar coordinate profiles, and displays them as a(More)
OBJECTIVES We prospectively compared dipyridamole single-photon emission computed tomography (SPECT) imaging with Tc-99m sestamibi and Tc-99m tetrofosmin for the detection of reversible perfusion defects in patients with mild-to-moderate coronary artery disease. BACKGROUND Tc-99m tetrofosmin has a lower first-pass myocardial extraction fraction compared(More)