Erkan Mozioğlu

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We have evaluated the efficiency of the TK Rapid Mycobacterial Culture System in isolating mycobacteria from clinical samples and in susceptibility testing. The TK Medium indicates mycobacterial growth by changing its color from red to yellow. During a 1-year period, 16,303 clinical samples were inoculated to TK selective (TK SLC) and Löwenstein-Jensen(More)
Curcumin is the most important fraction of turmeric which is responsible for its biological activity. In this study, isolation and biological assessment of turmeric and curcumin have been discussed against standard bacterial and mycobacterial strains such as E.coli, S.aureus, E.feacalis, P.aeuroginosa, M.smegmatis, M.simiae, M.kansasii, M. terrae, M.szulgai(More)
The fatty acid composition of the seed oil of 23 Stachys taxa was analysed by GC/MS. The main compounds were found to be linoleic (27.1-64.3%), oleic (20.25-48.1%), palmitic (4.3-9.1%), stearic (trace to 5.2%) and 6-octadecynoic (2.2-34.1%) acids. The latter compound could be used as a chemotaxonomic marker of the genus Stachys. A cluster analysis was(More)
BACKGROUND Real-time PCR (qPCR) based methods, such as the Xpert MTB/RIF, are increasingly being used to diagnose tuberculosis (TB). While qualitative methods are adequate for diagnosis, the therapeutic monitoring of TB patients requires quantitative methods currently performed using smear microscopy. The potential use of quantitative molecular measurements(More)
Enumeration-based determination of DNA copy-concentration was assessed through an international comparison among national metrology institutes (NMIs) and designated institutes (DIs). Enumeration-based quantification does not require a calibration standard thereby providing a route to "absolute quantification", which offers the potential for reliable value(More)
Four multicaulin and miltirone-like phenanthrene derivatives were synthesised and evaluated as antituberculosis agents. The crucial step of the synthesis was Pschorr coupling of 4-(3-isopropyl-4-methoxyphenyl)-2-(2-aminophenyl)ethane (13) to give 2-isopropyl-3-methoxy-9,10-dihydrophenanthrene (9) and 4-isopropyl-3-methoxy-9,10-dihydrophenanthrene (9a).(More)
A fully water soluble 3-hydroxyflavone (3HF) derivative, N-(3-hydroxy-4'-flavonyl)-N,N,N-trimethylammonium sulfate (3HFNMe3) was synthesized. Investigation of its emissions at varying wavelengths revealed that it had three emission bands of normal (N(⁎)), anionic (A(⁎)) and tautomeric (T(⁎)), in ultrapure water. Recognition of single-stranded ten ssDNA(More)
Erkan MOZİOĞLU*, Müslüm AKGÖZ, Candan TAMERLER, Zühtü Tanıl KOCAGÖZ Molecular Biology, Biotechnology, and Genetics Research Center, İstanbul Technical University, İstanbul, Turkey Bioanalysis Laboratory, TÜBİTAK National Metrology Institute (UME), Kocaeli, Turkey Mechanical Engineering Department, University of Kansas, Lawrence, Kansas, USA Department of(More)
Preventing adulteration of meat and meat products with less desirable or objectionable meat species is important not only for economical, religious and health reasons, but also, it is important for fair trade practices, therefore, several methods for identification of meat and meat products have been developed. In the present study, ten different DNA(More)